Article
The allelic structure of common disease.
Human molecular genetics - 1 Oct 2002
Smith Desmond J, Lusis Aldons J
Abstract excerpt
A better understanding of the allelic structure of common human disease loci may help identification of the responsible genes, and is thus a topic of considerable practical importance. If few alleles at each locus account for the majority of disease risk, then screening for these causative factors will be greatly simplified. In contrast, if large numbers of independent alleles are responsible, dramatic...
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