Article
Mutant Rab24 GTPase is targeted to nuclear inclusions.
BMC cell biology - 25 Sept 2002
Maltese William A, Soule Gwendolyn, Gunning William, Calomeni Edward, Alexander Brandy
Abstract excerpt
BACKGROUND: Members of the Rab GTPase family regulate intracellular protein trafficking, but the specific function of Rab24 remains unknown. Several attributes distinguish this protein from other members of the Rab family, including a low intrinsic GTPase activity. RESULTS: The functions of other Rab proteins have been defined through the use of dominant-negative mutants with amino acid substitutions in the...
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