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Article

Cellular Chaperonin CCTγ Contributes to Rabies Virus Replication during Infection

2 May 2013

Abstract excerpt

Rabies, as the oldest known infectious disease, remains a serious threat to public health worldwide. The eukaryotic cytosolic chaperonin TRiC/CCT complex facilitates the folding of proteins through ATP hydrolysis. Here, we investigated the expression, cellular localization, and function of neuronal CCTγ during neurotropic rabies virus (RABV) infection using mouse N2a cells as a model. Following RABV infection, 24...

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PMID: 23637400
DOI: 10.1128/jvi.03186-12

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