Article
Interaction of d-tubocurarine analogs with mutant 5-HT(3) receptors.
Neuropharmacology - 1 Sept 2002
Yan Dong, White Michael M
Abstract excerpt
d-Tubocurarine is a potent competitive antagonist of both the muscle-type nicotinic acetylcholine receptor (AChR) and the serotonin type-3 receptor (5HT(3)R). We have previously used a series of structural analogs of d-tubocurarine to demonstrate that the ligand-binding domains of both receptors share common structural features. We have now extended these studies to examine the interaction of a series of...
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