Identification and comparative analysis of the peptidyl‐prolyl <i>cis/trans</i> isomerase repertoires of <i>H. sapiens, D. melanogaster, C. elegans, S. cerevisiae and Sz. pombe</i>

Abstract excerpt

The peptidyl-prolyl cis/trans isomerase (PPIase) class of proteins comprises three member families that are found throughout nature and are present in all the major compartments of the cell. Their numbers appear to be linked to the number of genes in their respective genomes, although we have found the human repertoire to be smaller than expected due to a reduced cyclophilin repertoire. We show here that whilst...

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