Article
A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.
The Journal of biological chemistry - 6 Dec 2002
Moore Kathryn J, El Khoury Joseph, Medeiros Lea A, Terada Kinya, Geula Changiz, Luster Andrew D, Freeman Mason W
Abstract excerpt
beta-Amyloid accumulation is associated with pathologic changes in the brain in Alzheimer's disease and has recently been identified in plaques of another chronic inflammatory disorder, atherosclerosis. The class B scavenger receptor, CD36, mediates binding of fibrillar beta-amyloid to cells of t...
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