Article
Use of Chlamydomonas reinhardtii mutants for anticancer drug screening.
Biochemical pharmacology - 1 Oct 2002
Maucourt Karine, Agarwal Manjul, René Brigitte, Fermandjian Serge
Abstract excerpt
We investigated the possibility of utilizing alga cells instead of mammalian cells for the screening of anticancer drugs. The alga cells grow in synthetic media whereas the mammalian cells require complex and more expensive media along with heavy investment and manpower. To assess the validity of this new approach, analysis of growth inhibition by antitumor agents was carried out jointly on a wall-less (cw15)...
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