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Article

Age-related increase of pulse pressure and gene polymorphisms in essential hypertension: a preliminary study.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2002

Mourad Jean-Jacques, Ducailar Guilhem, Rudnicki Annie, Lajemi Malika, Mimran Albert, Safar Michel E

Abstract excerpt

Genes may modulate the changes of blood pressure (BP) with age; this possibility has never been studied for the age-related increase of pulse pressure (PP), although in older populations, PP is considered the stronger mechanical factor predicting cardiovascular mortality. In humans, the presence of the mutant allele C of the angiotensin II (Ang II) AT(1)-receptor or of the mutant allele T of the eNOS G(298) T...

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Identifiers

PMID: 12228851
DOI: 10.3317/jraas.2002.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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