Article
Cardiovascular phenotype of young adults and angiotensinogen alleles.
Journal of hypertension - 1 Dec 2001
Sarzani R, Dessì-Fulgheri P, Mazzara D, Catalini R, Cola G, Bersigotti G, Siragusa N, Salvi F, Ercolani P, Spagnolo D, Zingaretti O, Serenelli M, Pupita M, Magni C M, Giantomassi L, Pasquini R, Gesuita R, Carle F, Rappelli A
Abstract excerpt
OBJECTIVES AND DESIGN: Angiotensinogen (AGT) gene variants influence angiotensinogen plasma levels in children and young adults. The angiotensinogen promoter (-6)A variant facilitates gene transcription in human tissues and it has been associated with high blood pressure in older adults. A young adult population can be used as a model to study genotype/phenotype associations between AGT (-6) variants and...
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