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Article

Regulation of kidney-specific Ksp-cadherin gene promoter by hepatocyte nuclear factor-1beta.

American journal of physiology. Renal physiology - 1 Oct 2002

Bai Yun, Pontoglio Marco, Hiesberger Thomas, Sinclair Angus M, Igarashi Peter

Abstract excerpt

Kidney-specific cadherin (Ksp-cadherin) is a tissue-specific member of the cadherin family that is expressed exclusively in the kidney and developing genitourinary tract. Recent studies have shown that the proximal 250 bp of the Ksp-cadherin gene promoter are sufficient to direct tissue-specific gene expression in vivo and in vitro. The proximal 120 bp of the promoter are evolutionarily conserved between mouse...

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PMID: 12217876
DOI: 10.1152/ajprenal.00128.2002

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