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Article

Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA.

The Journal of biological chemistry - 9 Oct 2015

Hajarnis Sachin S, Patel Vishal, Aboudehen Karam, Attanasio Massimo, Cobo-Stark Patricia, Pontoglio Marco, Igarashi Peter

Abstract excerpt

The transcription factor hepatocyte nuclear factor-1β (HNF-1β) regulates tissue-specific gene expression in the kidney and other epithelial organs. Mutations of HNF-1β produce kidney cysts, and previous studies have shown that HNF-1β regulates the transcription of cystic disease genes, including Pkd2 and Pkhd1. Here, we combined chromatin immunoprecipitation and next-generation sequencing (ChIP-Seq) with...

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Identifiers

PMID: 26292219
DOI: 10.1074/jbc.M115.670646
PMCID: PMC4598991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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