Article
The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells.
Developmental biology - 1 Sept 2002
Sadl Virginia, Jin Fuzi, Yu Joanna, Cui Shiying, Holmyard Douglas, Quaggin Susan, Barsh Greg, Cordes Sabine
Abstract excerpt
Molecular components of the glomerular filtration mechanism play critical roles in renal diseases. Many of these components are produced during the final stages of differentiation of glomerular visceral epithelial cells, also known as podocytes. While basic domain leucine zipper (bZip) transcription factors of the Maf subfamily have been implicated in cellular differentiation processes, Kreisler (Krml1/MafB), the...
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