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Article

Hydrophobic interactions at the Ccap position of the C-capping motif of alpha-helices.

Journal of molecular biology - 6 Sept 2002

Ermolenko Dmitri N, Thomas Susan T, Aurora Rajeev, Gronenborn Angela M, Makhatadze George I

Abstract excerpt

We investigated the possible role of residues at the Ccap position in an alpha-helix on protein stability. A set of 431 protein alpha-helices containing a C'-Gly from the Protein Data Bank (PDB) was analyzed, and the normalized frequencies for finding particular residues at the Ccap position, the average fraction of buried surface area, and the hydrogen bonding patterns of the Ccap residue side-chain were...

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PMID: 12215419
DOI: 10.1016/s0022-2836(02)00734-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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