Article
SIPS as a model to study age-related changes in proteolysis and aggregate formation
27 Jul 2017
Abstract excerpt
Aging is accompanied by the accumulation of cellular damage over time in response to stress, lifestyle and environmental factors ultimately leading to age-related diseases and death. Additionally, the number of senescent cells increases with age. Senescence is most likely not a static endpoint, it represents a series of hallmarks including morphological changes, alterations in protein turnover and accumulation of...
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