Article
ACT and UCH-L1 polymorphisms in Parkinson's disease and age of onset.
Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2002
Wang Jian, Zhao Chun-Ying, Si Yan-Mei, Liu Zhuo-Lin, Chen Biao, Yu Long
Abstract excerpt
alpha1-Antichymotrypsin (ACT) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) have been suggested as susceptibility factors for Parkinson's disease (PD). We replicated these findings in a Chinese case-control sample consisting of 160 PD cases and 160 carefully matched control subjects. Genotypes were determined using polymerase chain reaction and BstN1 or Rsa1 restriction enzyme assay. Analysis showed no...
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