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Article

Core promoter mutations (A(1762)T and G(1764)A) and viral genotype in chronic hepatitis B and hepatocellular carcinoma in Guangxi, China.

Journal of medical virology - 1 Sept 2002

Fang Zhong-Liao, Yang Jinye, Ge Xianmin, Zhuang Hui, Gong Jian, Li Rongcheng, Ling Roger, Harrison Tim J

Abstract excerpt

Hepatitis B viruses (HBV) with core promoter mutations (A(1762)T, G(1764)A) were found in a previous study to be highly prevalent in patients from Guangxi, China with hepatocellular carcinoma (HCC). The aim of this study was to determine whether the mutations are prevalent in areas of Guangxi with high and lower incidences of HCC and whether they are associated with other severe sequelae of chronic hepatitis B,...

Topics

Base Sequence
Carcinoma, Hepatocellular
China
DNA, Viral
Genotype
Hepatitis B Core Antigens
Hepatitis B, Chronic
Humans
Liver Neoplasms
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis

Prevalence

Promoter Regions, Genetic

Protein Precursors

Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 12210428
DOI: 10.1002/jmv.10167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12210428-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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