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Article

Viral Factors and Outcomes of Chronic HBV Infection

1 Jan 2011

Abstract excerpt

Viral factors associated with outcome of chronic hepatitis B virus (HBV) infection include hepatitis B e antigen status, HBV DNA, genotype, and HBV variants. Mutations in the HBV core promoter region have been shown to be independently associated with hepatocellular carcinoma (HCC). The most common core promoter mutations involve a double substitution A1762T and G1764A (TA). Besides TA mutations, several other...

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PMID: 21212756
DOI: 10.1038/ajg.2010.404

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