Article
Mutation at minisatellite locus DYF155S1: allele length mutation rate is affected by age of progenitor.
Electrophoresis - 1 Aug 2002
Andreassen Rune, Lundsted Jan, Olaisen Bjørnar
Abstract excerpt
A father/son material consisting of 1071 pairs was screened for de novo allele length mutation in locus DYF155S1. Six hundred of these pairs were also analyzed in locus DYF155S1 to detect de novo mutations in the minisatellite variant repeat (MVR)-code not resulting in a length change ("boundary switch" mutations). A modified MVR-polymerase chain reaction (PCR) method was used for this purpose. Twenty-seven de...
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