Article
Organ-specific distribution of CD4+ T1/ST2+ Th2 cells in Leishmania major infection.
European journal of immunology - 1 Sept 2002
Kropf Pascale, Bickle Quentin, Herath Shanti, Klemenz Roman, Müller Ingrid
Abstract excerpt
Activated CD4(+) T helper cells (Th) comprise at least two functionally distinct subsets, Th1 and Th2, which mediate different immunological effector functions. Experimental leishmaniasis is widely used to study the effector function of Th cell subsets in vivo. Healing and nonhealing Leishmania major infections have been correlated with polarized Th1 and Th2 responses, respectively. In the study presented here, a...
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