Article
Analysis of T helper cell responses during infection with Leishmania amazonensis.
The American journal of tropical medicine and hygiene - 1 Apr 2002
Ji Jiaxiang, Sun Jiaren, Qi Hai, Soong Lynn
Abstract excerpt
Most inbred strains of mice are susceptible to Leishmania amazonensis infection and develop progressive cutaneous lesions. However, the role of Th subsets in the disease and the molecular basis of pathogenesis are unclear. To address this issue, we examined the frequency of cytokine-producing CD4+ T cells and the profile of alphabeta T cell receptor (TCR) usage in infected BALB/c mice. At different infection...
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