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Article

Resistance to Leishmania major induced by tolerance to a single antigen.

Science (New York, N.Y.) - 18 Oct 1996

Julia V, Rassoulzadegan M, Glaichenhaus N

Abstract excerpt

In mice, susceptibility to Leishmania major is associated with the early expansion of T helper 2 cells (TH2) cells, but nothing is known of the specificity of these cells. A previously identified antigen, Leishmania homolog of receptors for activated C kinase (LACK), was found to be the focus of this initial response. Mice made tolerant to LACK by the transgenic expression of the antigen in the thymus exhibited...

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Identifiers

PMID: 8832890
DOI: 10.1126/science.274.5286.421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Resistance to Leishmania major induced by tolerance to a single antigen.PMID 8832890Read ↗

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