Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the CYP1B1 gene have higher risk for prostate cancer.

Biochemical and biophysical research communications - 30 Aug 2002

Tanaka Yuichiro, Sasaki Masahiro, Kaneuchi Masanori, Shiina Hiroaki, Igawa Mikio, Dahiya Rajvir

Abstract excerpt

Various carcinogenic factors including estrogen metabolites play a role in malignant transformation. These metabolites are formed in part, as a result of the hydroxylation activity of cytochrome P450 (CYP) 1B1. Variant forms of this enzyme have been shown to enhance its activity, and thus, we hypothesize that single nucleotide polymorphisms of the CYP1B1 gene can be a risk factor for prostate cancer. To test this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Codon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1B1

Share to Cytochrome P-450 Enzyme System

Share to Introns

Share to Models, Genetic

Share to Prostatic Neoplasms

Source

Identifiers

PMID: 12200121
DOI: 10.1016/s0006-291x(02)02004-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the CYP1B1 gene have higher risk for prostate cancer.PMID 12200121Read ↗

Cytochrome P1B1 (CYP1B1) polymorphisms and cancer risk: a meta-analysis of 52 studies.Semantic proximity Read ↗

CYP1B1 gene polymorphisms have higher risk for endometrial cancer, and positive correlations with estrogen receptor alpha and estrogen receptor beta expressions.Semantic proximity Read ↗

Genetic polymorphisms in cytochrome P4501B1 and susceptibility to head and neck cancer.Semantic proximity Read ↗

Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: a meta-analysis.Semantic proximity Read ↗

CYP1B1 polymorphisms and susceptibility to prostate cancer: a meta-analysis.Semantic proximity Read ↗

Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men.Semantic proximity Read ↗

Association of CYP1B1 genetic polymorphism with incidence to breast and lung cancer.Semantic proximity Read ↗

CYP1B1 variants are associated with prostate cancer in non-Hispanic and Hispanic Caucasians.Semantic proximity Read ↗

The CYP1B1 Leu432Val polymorphism and risk of urinary system cancers.Semantic proximity Read ↗

Three polymorphisms in cytochrome P450 1B1 (CYP1B1) gene and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Prostate cancer risk and aggressiveness associated with the CYP1B1 4326C/G (Leu432Val) polymorphism: a meta-analysis of 2788 cases and 2968 controls.Semantic proximity Read ↗

Polymorphisms in the CYP1B1 gene are associated with increased risk of prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.