Aspects of the Complement System in New Era of Xenotransplantation

Abstract excerpt

)-KO pigs, hyperacute rejection appeared to no longer be a problem. However, the origin of xeno-rejection continues to be a controversial topic, including small amounts of antibodies and subsequent activation of the graft endothelium, the complement recognition system and the coagulation systems. The complement is activated via the classical pathway by non-Gal/H-D/Sda antigens and by ischemia-reperfusion injury...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Organ Transplantation Techniques and Outcomes
• Share to Pancreatic function and diabetes
• Share to Xenotransplantation and immune response