Article
An endothelial proinflammatory phenotype precedes the development of the engraftment syndrome after autologous Hct.
Bone marrow transplantation - 1 May 2022
Moreno-Castaño Ana Belén, Palomo Marta, Torramadé-Moix Sergi, Martinez-Sanchez Julia, Ramos Alex, Molina Patricia, Pino Marc, Gómez-Ramírez Pilar, Bonastre Laura, Solano Maria Teresa, Escolar Ginés, Rovira Montserrat, Rodríguez-Lobato Luis Gerardo, Gutiérrez-García Gonzalo, Carreras Enric, Fernández-Avilés Francesc, Diaz-Ricart Maribel
Abstract excerpt
Engraftment syndrome (ES) is a common complication after autologous hematopoietic cell transplantation (auto-HCT) whose pathophysiological substrate remains unclear. We investigated whether endothelial damage could contribute to ES. Circulating ECs-damage biomarkers were measured in plasma from patients with (ES; n = 14) or without ES (non-ES; n = 20), collected at different time points: before HCT, 5 (S5) and 10...
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