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Article

Analysis of the Mechanism for Chromatin Remodeling in Embryos Reconstructed by Somatic Nuclear Transfer1

1 Sept 2002

Abstract excerpt

The objective of the present study was to understand the molecular/biochemical nature of chromatin remodeling that occurs in the somatic nuclei transferred into oocytes. We produced the reconstructed mouse embryos by two different protocols of nuclear transfer. The nucleus of a cumulus cell was transferred into enucleated unfertilized oocytes (transferred before activation, TA protocol) or activated oocytes...

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PMID: 12193382
DOI: 10.1095/biolreprod.101.000612

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