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Article

Evolution of a VNTR located within the promoter region of the thiopurine methyltransferase gene: inferences from population and sequence data.

Human genetics - 1 Aug 2002

Alves Sandra, Amorim António, Prata Maria João

Abstract excerpt

The promoter region of the human thiopurine methyltransferase (TPMT) gene contains a variable number of tandem repeats (VNTR) with three kind of motifs (A, B, and C) differing by the length of the unit core and nucleotide sequence. We have studied the structural variation within the VNTR alleles in two human populations and in samples from gorillas and chimpanzees. In humans, no intermingling of motifs was...

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Identifiers

PMID: 12189491
DOI: 10.1007/s00439-002-0784-5

Genes

TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Evolution of a VNTR located within the promoter region of the thiopurine methyltransferase gene: inferences from population and sequence data.PMID 12189491Read ↗

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