Article
The apparent enhancement of CpG transversions in primate lineage is a consequence of multiple replacements.
Journal of bioinformatics and computational biology - 1 Jun 2014
Borštnik Branko, Pumpernik Danilo
Abstract excerpt
We claim that the apparently enhanced CpG transversions in the form CpG to CpC/GpG or to ApG/CpT are caused by the hypermutable CpG to CpA/TpG transition. The nucleotide replacement counts obtained from the human/chimpanzee/gorilla/orangutan sequence alignments representing the replacements due to the evolutionary species divergence and the results of 1000 genomes project that provide us with the differences due...
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