Article
Rare mutations of the DMBT1 gene in human astrocytic gliomas.
Oncogene - 29 Aug 2002
Mueller Wolf, Mollenhauer Jan, Stockhammer Florian, Poustka Annemarie, von Deimling Andreas
Abstract excerpt
The Deleted in Malignant Brain Tumors 1 gene (DMBT1) has been proposed as a tumor suppressor gene candidate in human brain tumors, based on the observation of homozygous deletions affecting the DMBT1 region or part of the gene. In order to support this hypothesis, we performed a mutational analysis of the entire coding region of DMBT1, employing SSCP analysis and direct DNA sequencing in a series of 79 astrocytic...
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