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Article

T1653 mutation in the box alpha increases the risk of hepatocellular carcinoma in patients with chronic hepatitis B virus genotype C infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jan 2006

Ito Kiyoaki, Tanaka Yasuhito, Orito Etsuro, Sugiyama Masaya, Fujiwara Kei, Sugauchi Fuminaka, Kato Takanobu, Tokita Hajime, Izumi Namiki, Kato Michio, Yuen Man-Fung, Lai Ching-Lung, Gish Robert G, Ueda Ryuzo, Mizokami Masashi

Abstract excerpt

BACKGROUND: Most patients with chronic hepatitis B virus infection become carriers of inactive virus after hepatitis B e antigen seroconversion; however, a subgroup of patients have persistent abnormal transaminase levels and develop hepatocellular carcinoma after seroconversion. METHODS: In an age-matched case-control study, 40 carriers of inactive virus (mean age+/-standard deviation [SD], 50.9 +/- 11.1 years),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16323084
DOI: 10.1086/498522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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