Article
Diaphragm contractile dysfunction in MyoD gene-inactivated mice.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Sept 2002
Staib Jessica L, Swoap Steven J, Powers Scott K
Abstract excerpt
MyoD is one of four myogenic regulatory factors found exclusively in skeletal muscle. In an effort to better understand the role that MyoD plays in determining muscle contractile properties, we examined the effects of MyoD deletion on both diaphragmatic contractile properties and myosin heavy chain (MHC) phenotype. Regions of the costal diaphragm from wild-type and MyoD knockout [MyoD (-/-)] adult male BALB/c...
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