Article
[Consequences of clinical genetic analysis of RET proto-oncogene].
Wiadomosci lekarskie (Warsaw, Poland : 1960) - 1 Jan 2001
Włoch J, Wygoda Z, Wiench M, Gubała E, Kula D, Oczko M, Lange D, Jarzab B
Abstract excerpt
Preliminary results of treatment of inherited medullary thyroid carcinoma, diagnosed primarily with genetic analysis of mutation of protooncogene RET are presented. Among 16 carriers of mutation identical with mutation diagnosed earlier in proband, there were 4 patients with clinically obvious medullary thyroid carcinoma and 12 asymptomatic carriers. In all patients, in whom calcitonin level was increased...
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