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Article

Characterization of V804M-mutated RET proto-oncogene associated with familial medullary thyroid cancer, report of the largest Turkish family.

Journal of endocrinological investigation - 1 May 2015

Basaran M N, Tuna M M, Karakılıç E, Doğan B A, İmga N N, Berker D, Güler S

Abstract excerpt

PURPOSE: Analysis of the RET proto-oncogen is very important for diagnosis and prognosis of medullary thyroid cancer (MTC). Genotype-phenotype correlation is also well known. Here we report features of the largest known family in Turkey with the V804M-mutated RET proto-oncogene. METHODS: Thirty members from three generations were evaluated. A RET proto-oncogen mutation, calcitonin (Ct) measurement and thyroid...

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Share to Carcinoma, Medullary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25501606
DOI: 10.1007/s40618-014-0224-0

Genes

RET

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