[Surgical management of hereditary medullary carcinoma of the thyroid in patients with "RET" proto-oncogene mutation].

Abstract excerpt

The authors report their results in 64 individuals belonging to 11 families with MEN 2 and familial medullary carcinoma of thyroid (CMT) syndromes. They show amplification and restriction techniques, type, site and incidence of genetic alteration in the observed cases; besides they illustrate the adopted surgical management related to the mutation. They stress the concept that genetic test allows to detect the...

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