Article
The Heritability of Breast Cancer among Women in the Nordic Twin Study of Cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2016
Möller Sören, Mucci Lorelei A, Harris Jennifer R, Scheike Thomas, Holst Klaus, Halekoh Ulrich, Adami Hans-Olov, Czene Kamila, Christensen Kaare, Holm Niels V, Pukkala Eero, Skytthe Axel, Kaprio Jaakko, Hjelmborg Jacob B
Abstract excerpt
BACKGROUND: Family history is an established risk factor for breast cancer. Although some important genetic factors have been identified, the extent to which familial risk can be attributed to genetic factors versus common environment remains unclear. METHODS: We estimated the familial concordance and heritability of breast cancer among 21,054 monozygotic and 30,939 dizygotic female twin pairs from the Nordic...
Topics
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Breast Neoplasms
- Cohort Studies
- Denmark
- Female
- Finland
- Follow-Up Studies