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Article

Documenting ancient DNA quality via alpha satellite amplification and assessment of clone sequence diversity.

Journal of applied genetics - 1 Jan 2002

Pusch Carsten M, Kayademir Tuncay, Prangenberg Kurt, Conard Nicholas J, Czarnetzki Alfred, Blin Nikolaus

Abstract excerpt

C/G-->T/A nucleotide alterations have been shown to hamper the straightforward interpretation of mitochondrial DNA sequence data derived from ancient tissues. Attempting to characterise this finding with respect to nuclear DNA, we contrasted two established protocols: (i) an enzymatic repair of damaged DNA, thereby translating and closing nicks in the DNA, and (ii) the application of N-phenacylthiazolium bromide,...

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PMID: 12177525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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