Article
Endogenous and exogenous glucocorticoid regulation of ENaC mRNA expression in developing kidney and lung.
American journal of physiology. Cell physiology - 1 Sept 2002
Nakamura Kenzo, Stokes John B, McCray Paul B
Abstract excerpt
Lung liquid absorption at birth is crucial for the successful onset of respiration. Na absorption by the renal collecting duct plays an important role in renal fluid and electrolyte homeostasis during the early postnatal period. The epithelial Na channel (ENaC) plays a central role in mediating these functions, and its subunit expression is developmentally regulated in a temporal and tissue specific pattern....
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