Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The patterns of wingless, decapentaplegic, and tinman position the Drosophila heart.

Mechanisms of development - 1 Jun 2002

Lockwood Wendy K, Bodmer Rolf

Abstract excerpt

Two secreted signaling molecules, wingless (wg) and decapentaplegic (dpp), are required to specify the heart in Drosophila. wg and dpp are also required to specify other cell types within the mesoderm and in many other regions of the embryo. Because the spatial patterns of wg and dpp are dynamic, different populations of mesodermal cells are exposed to different combinations of wg and/or dpp at different times....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Heart
Share to In Situ Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesoderm

Share to Proto-Oncogene Proteins

Share to Repressor Proteins

Share to Trans-Activators

Share to Wnt1 Protein

Source

Identifiers

PMID: 12175486
DOI: 10.1016/s0925-4773(02)00044-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The patterns of wingless, decapentaplegic, and tinman position the Drosophila heart.PMID 12175486Read ↗

Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila.Semantic proximity Read ↗

Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis.Semantic proximity Read ↗

The wingless signaling pathway is directly involved in Drosophila heart development.Semantic proximity Read ↗

Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5.Semantic proximity Read ↗

The gene tinman is required for specification of the heart and visceral muscles in Drosophila.Semantic proximity Read ↗

Heart development in Drosophila requires the segment polarity gene wingless.Semantic proximity Read ↗

Gata factor Pannier is required to establish competence for heart progenitor formation.Semantic proximity Read ↗

Akirin is critical for early tinman induction and subsequent formation of the heart in Drosophila melanogaster.Semantic proximity Read ↗

Tbx20-related genes, mid and H15, are required for tinman expression, proper patterning, and normal differentiation of cardioblasts in Drosophila.Semantic proximity Read ↗

Molecular integration of inductive and mesoderm-intrinsic inputs governs even-skipped enhancer activity in a subset of pericardial and dorsal muscle progenitors.Semantic proximity Read ↗

A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila.Semantic proximity Read ↗

Developmental paradigms in heart disease: insights from tinman.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.