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Article

Targeted assembly of short sequence reads.

PloS one - 11 May 2011

Warren René L, Holt Robert A

Abstract excerpt

As next-generation sequence (NGS) production continues to increase, analysis is becoming a significant bottleneck. However, in situations where information is required only for specific sequence variants, it is not necessary to assemble or align whole genome data sets in their entirety. Rather, NGS data sets can be mined for the presence of sequence variants of interest by localized assembly, which is a faster,...

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PMID: 21589938
DOI: 10.1371/journal.pone.0019816
PMCID: PMC3092772

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