Article
Distribution of p53 codon 72 polymorphisms in ovarian tumour patients and their prognostic significance in ovarian cancer patients.
Anticancer research - 1 Jan 2000
Høgdall Estrid V S, Høgdall Claus K, Christensen Lise, Glud Eva, Blaakaer Jan, Bock Johannes E, Vuust Jens, Nørgaard-Pedersen Bent, Kjaer Susanne K
Abstract excerpt
BACKGROUND: The p53 gene is frequently mutated in various human tumours. In addition, single nucleotide polymorphisms are often observed in exons and introns of the p53 gene in normal tissues and tumours. MATERIALS AND METHODS: The prevalence of a polymorphism involving codon 72 of exon 4 in the p53 gene was studied in peripheral white blood cells and tumour tissues from Danish ovarian tumour patients and in...
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