Article
Aldehyde dehydrogenase-2 genotypes and HLA haplotypes in Japanese patients with esophageal cancer.
Oncology reports - 1 Jan 2000
Watanabe Seishiro, Sasahara Katsuyuki, Kinekawa Fumihiko, Uchida Naohito, Masaki Tsutomu, Kurokohchi Kazutaka, Murota Masayuki, Touge Tetsuo, Kawauchi Kazuyoshi, Oda Syuji, Kuriyama Shigeki
Abstract excerpt
The aim of this study was to examine how aldehyde dehydrogenase-2 (ALDH2) genotypes and human leukocyte antigen (HLA) haplotypes contribute to the risk for esophageal cancer. We examined ALDH2 genotypes and HLA haplotypes in 29 Japanese patients with esophageal cancer. The ratio of patients who experienced current or former intense vasodilatation upon consuming alcohol (flushing type) was much higher in...
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