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Article

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

Developmental biology - 15 Aug 2002

Mustonen Tuija, Tümmers Mark, Mikami Tadahisa, Itoh Nobuyuki, Zhang Niang, Gridley Thomas, Thesleff Irma

Abstract excerpt

Teeth develop as epithelial appendages, and their morphogenesis is regulated by epithelial-mesenchymal interactions and conserved signaling pathways common to many developmental processes. A key event during tooth morphogenesis is the transition from bud to cap stage when the epithelial bud is divided into specific compartments distinguished by morphology as well as gene expression patterns. The enamel knot, a...

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PMID: 12167404
DOI: 10.1006/dbio.2002.0734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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