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Recent Advances in the Understanding of Gonadotrope Lineage Differentiation in the Developing Pituitary

11 Nov 2024

Abstract excerpt

BACKGROUND: The pituitary gland is a vital endocrine organ regulating body homoeostasis through six hormone-secreting cell types. Among these, pituitary gonadotrope cells are essential for reproductive function. Throughout pituitary ontogenesis, gonadotrope cells differentiate in a stepwise process, involving both morphogenic cues and transcription factors, which drives specification of progenitor cells into...

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PMID: 39527929
DOI: 10.1159/000542513

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