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Electric Field-Induced Molecular Vibration for Noninvasive, High-Efficiency DNA Transfection

9 Mar 2004

Abstract excerpt

Gene delivery is an essential research tool for elucidating gene structure, regulation, and function in biomedical research and is the technological basis for gene therapy. However, the application of nonviral vectors in mammalian cell transfection and gene therapy is limited in that current methods require large amounts of exogenous DNA and/or exhibit high cytotoxicity and low transfection efficiency in primary...

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PMID: 15093191
DOI: 10.1016/j.ymthe.2004.01.017

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