Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Understanding Clubfoot: Integrating Historical Origins, Embryologic Foundations, Epidemiology and Etiology-A Review.

Birth defects research - 1 Nov 2025

Saran J S R G, Devdass Varun, Anand Durai

Abstract excerpt

PURPOSE: Congenital talipes equinovarus (CTEV) or idiopathic clubfoot, is a common yet complex congenital musculoskeletal deformity characterized by cavus, adductus, varus and equinus components. Despite advances in conservative and surgical management, recurrence and long-term functional limitations remain unresolved challenges. This review aims to provide an integrative synthesis of the historical evolution,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clubfoot
Share to Genetic Predisposition to Disease
Share to History, 20th Century

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 41239882
DOI: 10.1002/bdr2.2543

Genes

PITX1
TBX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Understanding Clubfoot: Integrating Historical Origins, Embryologic Foundations, Epidemiology and Etiology-A Review.PMID 41239882Read ↗

Genetics, epidemiology and management of clubfoot and related disordersSemantic proximity Read ↗

Genetics of clubfoot; recent progress and future perspectives.Semantic proximity Read ↗

Genotype-phenotype correlation in clubfoot (talipes equinovarus).Semantic proximity Read ↗

Trends in congenital clubfoot prevalence and co-occurring anomalies during 1994-2021 in Denmark: A nationwide register-based study of 1,315,282 live born infantsSemantic proximity Read ↗

Congenital talipes equinovarus (clubfoot)Semantic proximity Read ↗

Update on clubfoot: etiology and treatment.Semantic proximity Read ↗

SOX9 overexpression plays a potential role in idiopathic congenital talipes equinovarusSemantic proximity Read ↗

Epidemiology and genetic theories in the etiology of congenital talipes equinovarus.Semantic proximity Read ↗

A thorough analysis of data on the correlation between COL9A1 polymorphisms and the susceptibility to congenital talipes equinovarus: a meta-analysis.Semantic proximity Read ↗

Skeletal muscle abnormalities and genetic factors related to vertical talus.Semantic proximity Read ↗

Genetics of clubfoot.Semantic proximity Read ↗

Copy number analysis of 413 isolated talipes equinovarus patients suggests role for transcriptional regulators of early limb developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.