Article
HLA DQ alleles and interleukin-10 polymorphism associated with Chlamydia trachomatis-related tubal factor infertility: a case-control study.
Human reproduction (Oxford, England) - 1 Aug 2002
Kinnunen A H, Surcel H-M, Lehtinen M, Karhukorpi J, Tiitinen A, Halttunen M, Bloigu A, Morrison R P, Karttunen R, Paavonen J
Abstract excerpt
BACKGROUND: The relationship between Chlamydia trachomatis tubal factor infertility (TFI) and the host's immunoregulatory genes was studied. METHODS: Cell-mediated immune responses to C. trachomatis and chlamydial heat shock protein (CHSP60) were determined by lymphocyte proliferation assay. HLA-DQ alleles and interleukin-10 (IL-10) promoter polymorphism (-1082 A/G) were analysed in 52 TFI cases and in 61...
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