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Chlamydia trachomatis Infection and Anti-Hsp60 Immunity: The Two Sides of the Coin

27 Aug 2009

Abstract excerpt

Chlamydia trachomatis (CT) infection is one of the most common causes of reproductive tract diseases and infertility. CT-Hsp60 is synthesized during infection and is released in the bloodstream. As a consequence, immune cells will produce anti-CT-Hsp60 antibodies. Hsp60, a ubiquitous and evolutionarily conserved chaperonin, is normally sequestered inside the cell, particularly into mitochondria. However, upon...

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PMID: 19714222
DOI: 10.1371/journal.ppat.1000552

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