Article
Evolutionary divergence of the archaeal aspartyl-tRNA synthetases into discriminating and nondiscriminating forms.
The Journal of biological chemistry - 4 Oct 2002
Tumbula-Hansen Debra, Feng Liang, Toogood Helen, Stetter Karl O, Söll Dieter
Abstract excerpt
Asparaginyl-tRNA (Asn-tRNA) is generated in nature via two alternate routes, either direct acylation of tRNA with asparagine by asparaginyl-tRNA synthetase (AsnRS) or in a two-step pathway that requires misacylated Asp-tRNA(Asn) as an intermediate. This misacylated aminoacyl-tRNA is formed by a n...
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