Article
The role of hemochromatosis susceptibility gene mutations in protecting against iron deficiency in celiac disease.
Gastroenterology - 1 Aug 2002
Butterworth Jeffrey R, Cooper Brian T, Rosenberg William M C, Purkiss Michael, Jobson Shirley, Hathaway Mark, Briggs David, Howell W Martin, Wood Gordon M, Adams David H, Iqbal Tariq H
Abstract excerpt
BACKGROUND & AIMS: Celiac disease and hereditary hemochromatosis are common HLA-defined conditions in northwestern Europe. We sought to determine whether there is a genetic relationship between the 2 diseases and if hemochromatosis susceptibility gene (HFE) mutations are protective against iron deficiency in celiac disease. METHODS: Polymerase chain reaction amplification using sequence-specific primers capable...
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