Celtic origin of the C282Y mutation of hemochromatosis.

doi:10.1006/bcmd.1998.0212

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Article

Celtic origin of the C282Y mutation of hemochromatosis.

Blood cells, molecules & diseases - 1 Dec 1998

Lucotte G

Abstract excerpt

The C282Y mutation in the HFE gene is the main mutation causing hemochromatosis, and C282Y frequencies have been reported for various European populations. The aim of this review is to compile the Y allele frequencies of the C282Y mutation for twenty European populations. The most elevated value...

Topics

Europe
Gene Frequency
Genes, MHC Class I
HLA Antigens
Hemochromatosis
Hemochromatosis Protein
Histocompatibility Antigens Class I
Humans
Membrane Proteins
Mutation
Tyrosine

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