Article
Phosphorylation of the Pseudomonas aeruginosa response regulator AlgR is essential for type IV fimbria-mediated twitching motility.
Journal of bacteriology - 1 Aug 2002
Whitchurch Cynthia B, Erova Tatiana E, Emery Jacqui A, Sargent Jennifer L, Harris Jonathan M, Semmler Annalese B T, Young Michael D, Mattick John S, Wozniak Daniel J
Abstract excerpt
The response regulator AlgR is required for both alginate biosynthesis and type IV fimbria-mediated twitching motility in Pseudomonas aeruginosa. In this study, the roles of AlgR signal transduction and phosphorylation in twitching motility and biofilm formation were examined. The predicted phosphorylation site of AlgR (aspartate 54) and a second aspartate (aspartate 85) in the receiver domain of AlgR were...
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